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An evolutionarily conserved mutual interdependence between Aire and microRNAs in promiscuous gene expression

The establishment and maintenance of central tolerance depends to a large extent on the ability of medullary thymic epithelial cells to express a variety of tissue-restricted antigens, the so-called promiscuous gene expression (pGE). Autoimmune regulator (Aire) is to date the best characterised tran...

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Detalhes bibliográficos
Main Authors: Ucar, Olga, Tykocinski, Lars-Oliver, Dooley, James, Liston, Adrian, Kyewski, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816332/
https://ncbi.nlm.nih.gov/pubmed/23589212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201343343
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