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The site of allergen expression in hematopoietic cells determines the degree and quality of tolerance induced through molecular chimerism
The transplantation of allergens (e.g. Phl p 5 or Bet v 1) expressed on BM cells as membrane-anchored full-length proteins leads to permanent tolerance at the T-cell, B-cell, and effector-cell levels. Since the exposure of complete allergens bears the risk of inducing anaphylaxis, we investigated he...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3816328/ https://ncbi.nlm.nih.gov/pubmed/23765421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201243277 |
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