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Poly(ADP-ribosyl)ation regulates insulator function and intra-chromosomal interactions in Drosophila

Insulators mediate inter- and intra-chromosomal contacts to regulate enhancer-promoter interactions and establish chromosome domains. The mechanisms by which insulator activity can be regulated to orchestrate changes in the function and three-dimensional arrangement of the genome remain elusive. Her...

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Hlavní autoři: Ong, Chin-Tong, Van Bortle, Kevin, Ramos, Edward, Corces, Victor G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816015/
https://ncbi.nlm.nih.gov/pubmed/24055367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.08.052
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