The Drosophila Numb protein inhibits signaling of the Notch receptor during cell-cell interaction in sensory organ lineage.

Specification of unequal daughter cell fates in the Drosophila external sense organ lineage requires asymmetric localization of the intrinsic determinant Numb as well as cell-cell interactions mediated by the Delta ligand and Notch receptor. Previous genetic studies indicated that numb acts upstream...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Frise, E, Knoblich, J A, Younger-Shepherd, S, Jan, L Y, Jan, Y N
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38160/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8876239/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.21.11925
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