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Rescue of an hTERT Mutant Defective in Telomere Elongation by Fusion with hPot1

The protein hPot1 shares homology with telomere-binding proteins in lower eukaryotes and associates with single-stranded telomeric DNA in vitro as well as colocalizing with telomere-binding proteins in vivo. We now show that hPot1 is coimmunoprecipitated with telomeric DNA and that stable expression...

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Detalhes bibliográficos
Main Authors: Armbruster, Blaine N., Linardic, Corinne M., Veldman, Tim, Bansal, Niharika P., Downie, Diane L., Counter, Christopher M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC381596/
https://ncbi.nlm.nih.gov/pubmed/15060173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.8.3552-3561.2004
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