Genomic Aberrations Occurring in Subsets of Serrated Colorectal Lesions but not Conventional Adenomas

A subset of aggressive colorectal cancers exhibit BRAF mutation, MLH1 methylation, and a CpG island methylator phenotype (CIMP), but precursors are poorly established. In this study, we determined the status of these markers in colorectal polyps and evaluated associated risk factors. The study inclu...

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Autori principali: Burnett-Hartman, Andrea N., Newcomb, Polly A., Potter, John D., Passarelli, Michael N., Phipps, Amanda I., Wurscher, Michelle A., Grady, William M., Zhu, Lee-Ching, Upton, Melissa P., Makar, Karen W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815695/
https://ncbi.nlm.nih.gov/pubmed/23539450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-3462
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