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Deep resequencing of 17 glutamate system genes identifies rare variants in DISC1 and GRIN2B affecting risk of opioid dependence

The N-methyl-D-aspartate (NMDA) glutamate receptors play important roles in the pathophysiology of substance dependence (SD), but no strong genetic evidence has associated common variants in NMDAR-related genes to SD. We hypothesized that rare variants (RVs) with minor allele frequency < 1% in th...

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Main Authors: Xie, Pingxing, Kranzler, Henry R., Krystal, John H., Farrer, Lindsay A., Zhao, Hongyu, Gelernter, Joel
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815683/
https://ncbi.nlm.nih.gov/pubmed/23855403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/adb.12072
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