APOE interacts with age to modify rate of decline in cognitive and brain changes in Alzheimer’s disease

BACKGROUND: To determine (1) whether age-standardized cognitive declines and brain morphometric change differ between Young-Old (YOAD) and Very-Old (VOAD) patients with Alzheimer’s disease (AD) and (2) whether apolipoprotein E (APOE) genotype modifies these neuropsychological and morphometric change...

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Autors principals: Chang, Yu-Ling, Fennema-Notestine, Christine, Holland, Dominic, McEvoy, Linda K., Stricker, Nikki H., Salmon, David P., Dale, Anders M., Bondi, Mark W.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815680/
https://ncbi.nlm.nih.gov/pubmed/23896613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2013.05.1763
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