Llwytho...

Preparation of Fully Synthetic Histone H3 reveals That Acetyl-Lysine 56 Facilitates Protein Binding within Nucleosomes

Post-translational modification (PTM) of histones plays a central role in genome regulation. Engineering histones with defined PTMs on one or multiple residues is crucial for understanding their function within nucleosomes and chromatin. We introduce a sequential native chemical ligation strategy su...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Shimko, John C., North, Justin A., Bruns, Aaron N., Poirier, Michael G., Ottesen, Jennifer J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815667/
https://ncbi.nlm.nih.gov/pubmed/21310161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.01.003
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