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Synthesis and Characterization of Mono-, Di-, and Tri-Polyethylene Glycol Chlorin e(6) Conjugates for the Photokilling of Human Ovarian Cancer Cells

Pegylated chlorin e(6) photosensitizers were synthesized with triethylene glycol attached at the ester bond(s) for a 1:1 conjugate at the 17(3)-position, a 2:1 conjugate at the 15(2)- and 17(3)-positions, and a 3:1 conjugate at the 13(1)-, 15(2)-, and 17(3)-positions. These chlorin sensitizers were...

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Detalhes bibliográficos
Main Authors: Kimani, Stanley, Ghosh, Goutam, Ghogare, Ashwini, Rudshteyn, Benjamin, Bartusik, Dorota, Hasan, Tayyaba, Greer, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815657/
https://ncbi.nlm.nih.gov/pubmed/23126407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo301889s
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