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Mesenchymal Stem Cells Ability to Generate Traction Stress in Response to Substrate Stiffness is Modulated by the Changing Extracellular Matrix Composition of the Heart During Development

In this study we present a novel method for studying cellular traction force generation and mechanotransduction in the context of cardiac development. Rat hearts from three distinct stage of development (fetal, neonatal and adult) were isolated, decellularized and characterized via mechanical testin...

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Detalhes bibliográficos
Main Authors: Gershlak, Joshua R., Resnikoff, Joshua IN, Sullivan, Kelly E, Williams, Corin, Wang, Raymond M., Black, Lauren D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815602/
https://ncbi.nlm.nih.gov/pubmed/23994333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2013.08.074
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