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Inhibition of GSK3α/β promotes increased pulmonary endothelial permeability to albumin by reactive oxygen/nitrogen species

Glycogen synthase kinase 3α/β (GSK3α/β) is a serine/threonine kinase that participates in numerous processes in many cell types. Importantly, the role of GSK3α/β in homeostatic maintenance of the pulmonary endothelial cell barrier to protein is not known. We tested the hypothesis that GSK3α/β regula...

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Detalhes bibliográficos
Main Authors: Neumann, Paul, Alsaffar, Hiba, Gertzberg, Nancy, Johnson, Arnold
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815498/
https://ncbi.nlm.nih.gov/pubmed/23770025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pupt.2013.06.001
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