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Uracil influences quorum sensing and biofilm formation in Pseudomonas aeruginosa and fluorouracil is an antagonist

Pseudomonas aeruginosa is an ubiquitous, opportunistic pathogen whose biofilms are notoriously difficult to control. Here we discover uracil influences all three known quorum‐sensing (QS) pathways of P. aeruginosa. By screening 5850 transposon mutants for altered biofilm formation, we identified sev...

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Bibliografske podrobnosti
Main Authors: Ueda, Akihiro, Attila, Can, Whiteley, Marvin, Wood, Thomas K.
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815422/
https://ncbi.nlm.nih.gov/pubmed/21261882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1751-7915.2008.00060.x
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