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Uracil influences quorum sensing and biofilm formation in Pseudomonas aeruginosa and fluorouracil is an antagonist

Pseudomonas aeruginosa is an ubiquitous, opportunistic pathogen whose biofilms are notoriously difficult to control. Here we discover uracil influences all three known quorum‐sensing (QS) pathways of P. aeruginosa. By screening 5850 transposon mutants for altered biofilm formation, we identified sev...

詳細記述

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書誌詳細
主要な著者: Ueda, Akihiro, Attila, Can, Whiteley, Marvin, Wood, Thomas K.
フォーマット: Artigo
言語:Inglês
出版事項: Blackwell Publishing Ltd 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815422/
https://ncbi.nlm.nih.gov/pubmed/21261882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1751-7915.2008.00060.x
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