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Bidirectional Lipid Droplet Velocities Are Controlled by Differential Binding Strengths of HCV Core DII Protein

Host cell lipid droplets (LD) are essential in the hepatitis C virus (HCV) life cycle and are targeted by the viral capsid core protein. Core-coated LDs accumulate in the perinuclear region and facilitate viral particle assembly, but it is unclear how mobility of these LDs is directed by core. Herei...

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Detalhes bibliográficos
Main Authors: Lyn, Rodney K., Hope, Graham, Sherratt, Allison R., McLauchlan, John, Pezacki, John Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815211/
https://ncbi.nlm.nih.gov/pubmed/24223760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078065
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