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γ-Secretase Components as Predictors of Breast Cancer Outcome
γ-secretase is a large ubiquitously expressed protease complex composed of four core subunits: presenilin, Aph1, PEN-2, and nicastrin. The function of γ-secretase in the cells is to proteolytically cleave various proteins within their transmembrane domains. Presenilin and Aph1 occur as alternative v...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3815159/ https://ncbi.nlm.nih.gov/pubmed/24223915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079249 |
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