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Alterations in the Cell Cycle in the Cerebellum of Hyperbilirubinemic Gunn Rat: A Possible Link with Apoptosis?
Severe hyperbilirubinemia causes neurological damage both in humans and rodents. The hyperbilirubinemic Gunn rat shows a marked cerebellar hypoplasia. More recently bilirubin ability to arrest the cell cycle progression in vascular smooth muscle, tumour cells, and, more importantly, cultured neurons...
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Format: | Artigo |
Sprache: | Inglês |
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Public Library of Science
2013
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3815147/ https://ncbi.nlm.nih.gov/pubmed/24223883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079073 |
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