A Mutation in the FHA Domain of Coprinus cinereus Nbs1 Leads to Spo11-Independent Meiotic Recombination and Chromosome Segregation

Nbs1, a core component of the Mre11-Rad50-Nbs1 complex, plays an essential role in the cellular response to DNA double-strand breaks (DSBs) and poorly understood roles in meiosis. We used the basidiomycete Coprinus cinereus to examine the meiotic roles of Nbs1. We identified the C. cinereus nbs1 gen...

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Main Authors: Crown, K. Nicole, Savytskyy, Oleksandr P., Malik, Shehre-Banoo, Logsdon, John, Williams, R. Scott, Tainer, John A., Zolan, Miriam E.
Formato: Artigo
Idioma:Inglês
Publicado: Genetics Society of America 2013
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Investigations
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815056/
https://ncbi.nlm.nih.gov/pubmed/24062528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.113.007906
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