Antibody-conjugated, dual-modal, near-infrared fluorescent iron oxide nanoparticles for antiamyloidgenic activity and specific detection of amyloid-β fibrils

Amyloid-β (Aβ) peptide is the main fibrillar component of plaque deposits found in brains affected by Alzheimer’s disease (AD) and is related to the pathogenesis of AD. Passive anti-Aβ immunotherapy has emerged as a promising approach for the therapy of AD, based on the administration of specific an...

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Detalhes bibliográficos
Main Authors: Skaat, Hadas, Corem-Slakmon, Enav, Grinberg, Igor, Last, David, Goez, David, Mardor, Yael, Margel, Shlomo
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2013
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814992/
https://ncbi.nlm.nih.gov/pubmed/24194640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S52833
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