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RNA–DNA differences in human mitochondria restore ancestral form of 16S ribosomal RNA

RNA transcripts are generally identical to the underlying DNA sequences. Nevertheless, RNA–DNA differences (RDDs) were found in the nuclear human genome and in plants and animals but not in human mitochondria. Here, by deep sequencing of human mitochondrial DNA (mtDNA) and RNA, we identified three R...

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Detalhes bibliográficos
Main Authors: Bar-Yaacov, Dan, Avital, Gal, Levin, Liron, Richards, Allison L., Hachen, Naomi, Rebolledo Jaramillo, Boris, Nekrutenko, Anton, Zarivach, Raz, Mishmar, Dan
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814879/
https://ncbi.nlm.nih.gov/pubmed/23913925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.161265.113
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