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Identification of Proteins at Active, Stalled, and Collapsed Replication Forks Using Isolation of Proteins on Nascent DNA (iPOND) Coupled with Mass Spectrometry

Both DNA and chromatin need to be duplicated during each cell division cycle. Replication happens in the context of defects in the DNA template and other forms of replication stress that present challenges to both genetic and epigenetic inheritance. The replication machinery is highly regulated by r...

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Main Authors: Sirbu, Bianca M., McDonald, W. Hayes, Dungrawala, Huzefa, Badu-Nkansah, Akosua, Kavanaugh, Gina M., Chen, Yaoyi, Tabb, David L., Cortez, David
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814742/
https://ncbi.nlm.nih.gov/pubmed/24047897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.511337
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