Disruption of the protein C inhibitor gene results in impaired spermatogenesis and male infertility

Protein C inhibitor (PCI) is a nonspecific, heparin-binding serpin (serine protease inhibitor) that inactivates many plasmatic and extravascular serine proteases by forming stable 1:1 complexes. Proteases inhibited by PCI include the anticoagulant activated protein C, the plasminogen activator uroki...

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Autors principals: Uhrin, Pavel, Dewerchin, Mieke, Hilpert, Mario, Chrenek, Peter, Schöfer, Christian, Zechmeister-Machhart, Margareta, Krönke, Gerhard, Vales, Anja, Carmeliet, Peter, Binder, Bernd R., Geiger, Margarethe
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2000
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC381472/
https://ncbi.nlm.nih.gov/pubmed/11120760
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