Impaired translational response and increased protein kinase PKR expression in T cells from lupus patients

Activation of peripheral blood T cells results in a rapid and substantial rise in translation rates and proliferation, but proliferation in response to mitogen stimulation is impaired in systemic lupus erythematosus (SLE). We have investigated translation rates and initiation factor activities in T...

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Bibliographic Details
Main Authors: Grolleau, Annabelle, Kaplan, Mariana J., Hanash, Samir M., Beretta, Laura, Richardson, Bruce
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2000
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC381471/
https://ncbi.nlm.nih.gov/pubmed/11120763
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