Identification of Strain-Specific B-cell Epitopes in Trypanosoma cruzi Using Genome-Scale Epitope Prediction and High-Throughput Immunoscreening with Peptide Arrays

BACKGROUND: The factors influencing variation in the clinical forms of Chagas disease have not been elucidated; however, it is likely that the genetics of both the host and the parasite are involved. Several studies have attempted to correlate the T. cruzi strains involved in infection with the clin...

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Detalhes bibliográficos
Main Authors: Mendes, Tiago Antônio de Oliveira, Reis Cunha, João Luís, de Almeida Lourdes, Rodrigo, Rodrigues Luiz, Gabriela Flávia, Lemos, Lucas Dhom, dos Santos, Ana Rita Rocha, da Câmara, Antônia Cláudia Jácome, Galvão, Lúcia Maria da Cunha, Bern, Caryn, Gilman, Robert H., Fujiwara, Ricardo Toshio, Gazzinelli, Ricardo Tostes, Bartholomeu, Daniella Castanheira
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814679/
https://ncbi.nlm.nih.gov/pubmed/24205430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002524
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