Increasing the complexity of chromatin: functionally distinct roles for replication-dependent histone H2A isoforms in cell proliferation and carcinogenesis

Replication-dependent histones are encoded by multigene families found in several large clusters in the human genome and are thought to be functionally redundant. However, the abundance of specific replication-dependent isoforms of histone H2A is altered in patients with chronic lymphocytic leukemia...

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Detalhes bibliográficos
Main Authors: Singh, Rajbir, Mortazavi, Amir, Telu, Kelly H., Nagarajan, Prabakaran, Lucas, David M., Thomas-Ahner, Jennifer M., Clinton, Steven K., Byrd, John C., Freitas, Michael A., Parthun, Mark R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Gene Regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814372/
https://ncbi.nlm.nih.gov/pubmed/23956221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt736
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