Biological evaluation of transdichloridoplatinum(II) complexes with 3- and 4-acetylpyridine in comparison to cisplatin

BACKGROUND: In our previous study we reported the synthesis and cytotoxicity of two trans-platinum(II) complexes: trans-[PtCl(2)(3-acetylpyridine)(2)] (1) and trans-[PtCl(2)(4-acetylpyridine)(2)] (2), revealing significant cytotoxic potential of 2. In order to evaluate the mechanism underlying biolo...

Full description

Saved in:
Bibliographic Details
Main Authors: Filipovic, Lana, Arandelovic, Sandra, Gligorijevic, Nevenka, Krivokuca, Ana, Jankovic, Radmila, Srdic-Rajic, Tatjana, Rakic, Gordana, Tesic, Zivoslav, Radulovic, Sinisa
Format: Artigo
Language:Inglês
Published: Versita, Warsaw 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814279/
https://ncbi.nlm.nih.gov/pubmed/24294179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2478/raon-2013-0050
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items