Dominantly inherited hyperinsulinism caused by a mutation in the sulfonylurea receptor type 1

ATP-sensitive potassium channels play a major role in linking metabolic signals to the exocytosis of insulin in the pancreatic β cell. These channels consist of two types of protein subunit: the sulfonylurea receptor SUR1 and the inward rectifying potassium channel Kir6.2. Mutations in the genes enc...

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Main Authors: Huopio, Hanna, Reimann, Frank, Ashfield, Rebecca, Komulainen, Jorma, Lenko, Hanna-Liisa, Rahier, Jaques, Vauhkonen, Ilkka, Kere, Juha, Laakso, Markku, Ashcroft, Frances, Otonkoski, Timo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2000
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC381424/
https://ncbi.nlm.nih.gov/pubmed/11018078
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