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Separation of silencing from perinuclear anchoring functions in yeast Ku80, Sir4 and Esc1 proteins

In budding yeast, the nuclear periphery forms a subcompartment in which telomeres cluster and SIR proteins concentrate. To identify the proteins that mediate chromatin anchorage to the nuclear envelope, candidates were fused to LexA and targeted to an internal GFP-tagged chromosomal locus. Their abi...

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Autores principales: Taddei, Angela, Hediger, Florence, Neumann, Frank R, Bauer, Christoph, Gasser, Susan M
Formato: Artigo
Lenguaje:Inglês
Publicado: 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC381416/
https://ncbi.nlm.nih.gov/pubmed/15014445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600144
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