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Endosomal acidification by Na(+)/H(+) exchanger NHE5 regulates TrkA cell-surface targeting and NGF-induced PI3K signaling
To facilitate polarized vesicular trafficking and signal transduction, neuronal endosomes have evolved sophisticated mechanisms for pH homeostasis. NHE5 is a member of the Na(+)/H(+) exchanger family and is abundantly expressed in neurons and associates with recycling endosomes. Here we show that NH...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3814139/ https://ncbi.nlm.nih.gov/pubmed/24006492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-06-0445 |
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