Local Gene Transfer of OPG Prevents Joint Damage and Disease Progression in Collagen-Induced Arthritis

This study examined the influence of osteoprotegerin (OPG) gene transfer on a murine collagen-induced arthritis model. A single periarticular injection of AAV-OPG or AAV-LacZ on the arthritic paw successfully incorporated the exogenous gene to the local tissue and resulted in marked transgene expres...

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Detalhes bibliográficos
Main Authors: Zhang, Qingguo, Gong, Weiming, Ning, Bin, Nie, Lin, Wooley, Paul H., Yang, Shang-You
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814078/
https://ncbi.nlm.nih.gov/pubmed/24222748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/718061
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