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Distinct Activities of the Related Protein Kinases Cdk1 and Ime2
In budding yeast, commitment to DNA replication during the normal cell cycle requires degradation of the cyclin-dependent kinase (CDK) inhibitor Sic1. The G1 cyclin-CDK complexes Cln1-Cdk1 and Cln2-Cdk1 initiate the process of Sic1 removal by directly catalyzing Sic1 phosphorylation at multiple site...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3814016/ https://ncbi.nlm.nih.gov/pubmed/17137646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2006.10.003 |
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