Role of the Cdc25A phosphatase in human breast cancer

The phosphatase Cdc25A plays an important role in cell cycle regulation by removing inhibitory phosphates from tyrosine and threonine residues of cyclin-dependent kinases, and it has been shown to transform diploid murine fibroblasts in cooperation with activated Ras. Here we show that Cdc25A is ove...

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Publicado en:	J Clin Invest
Autores principales:	Cangi, M. Giulia, Cukor, Barry, Soung, Peggy, Signoretti, Sabina, Moreira, Gilberto, Ranashinge, Moksha, Cady, Blake, Pagano, Michele, Loda, Massimo
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Clinical Investigation 2000
Materias:	Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC381390/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10995786/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI9174
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