SMG1 Identified as a Regulator of Parkinson’s Disease-Associated alpha-Synuclein through siRNA Screening

Synucleinopathies are a broad class of neurodegenerative disorders characterized by the presence of intracellular protein aggregates containing α-synuclein protein. The aggregated α-synuclein protein is hyperphosphorylated on serine 129 (S129) compared to the unaggregated form of the protein. While...

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Detalhes bibliográficos
Main Authors: Henderson-Smith, Adrienne, Chow, Donald, Meechoovet, Bessie, Aziz, Meraj, Jacobson, Sandra A., Shill, Holly A., Sabbagh, Marwan N., Caviness, John N., Adler, Charles H., Driver-Dunckley, Erika D., Beach, Thomas G., Yin, Hongwei, Dunckley, Travis
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3813773/
https://ncbi.nlm.nih.gov/pubmed/24204929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077711
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