Hematoporphyrin Monomethyl Ether-Mediated Photodynamic Therapy Selectively Kills Sarcomas by Inducing Apoptosis

We investigated the antitumor effect and mechanism of hematoporphyrin monomethyl ether-mediated photodynamic therapy (HMME-PDT) in sarcomas. Intracellular uptake of HMME by osteosarcoma cells (LM8 and K7) was time- and dose-dependent, while this was not observed for myoblast cells (C2C12) and fibrob...

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Main Authors: Zeng, Hui, Sun, Mengxiong, Zhou, Chenghao, Yin, Fei, Wang, Zhuoying, Hua, Yingqi, Cai, Zhengdong
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3813767/
https://ncbi.nlm.nih.gov/pubmed/24204937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077727
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