Predictors of CD4:CD8 Ratio Normalization and Its Effect on Health Outcomes in the Era of Combination Antiretroviral Therapy

BACKGROUND: HIV leads to CD4:CD8 ratio inversion as immune dysregulation progresses. We examined the predictors of CD4:CD8 normalization after combination antiretroviral therapy (cART) and determined whether normalization is associated with reduced progression to AIDS-defining illnesses (ADI) and de...

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Autori principali: Leung, Victor, Gillis, Jennifer, Raboud, Janet, Cooper, Curtis, Hogg, Robert S., Loutfy, Mona R., Machouf, Nima, Montaner, Julio S. G., Rourke, Sean B., Tsoukas, Chris, Klein, Marina B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3813720/
https://ncbi.nlm.nih.gov/pubmed/24204912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077665
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