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Host cell protein dynamics in recombinant CHO cells: Impacts from harvest to purification and beyond
During the production of recombinant protein products, such as monoclonal antibodies, manufacturers must demonstrate clearance of host cell impurities and contaminants to appropriate levels prior to use in the clinic. These include host cell DNA and RNA, product related contaminants such as aggregat...
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| Huvudupphovsmän: | , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Landes Bioscience
2013
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3813528/ https://ncbi.nlm.nih.gov/pubmed/23328085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/bioe.23382 |
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