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Latrunculin A Treatment Prevents Abnormal Chromosome Segregation for Successful Development of Cloned Embryos

Somatic cell nuclear transfer to an enucleated oocyte is used for reprogramming somatic cells with the aim of achieving totipotency, but most cloned embryos die in the uterus after transfer. While modifying epigenetic states of cloned embryos can improve their development, the production rate of clo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Terashita, Yukari, Yamagata, Kazuo, Tokoro, Mikiko, Itoi, Fumiaki, Wakayama, Sayaka, Li, Chong, Sato, Eimei, Tanemura, Kentaro, Wakayama, Teruhiko
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3813513/
https://ncbi.nlm.nih.gov/pubmed/24205216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078380
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