Preferential Lectin Binding of Cancer Cells upon Sialic Acid Treatment under Nutrient Deprivation

The terminal monosaccharide of glycoconjugates on a eukaryotic cell surface is typically a sialic acid (Neu5Ac). Increased sialylation usually indicates progression and poor prognosis of most carcinomas. Here, we utilize two human mammary epithelial cell lines, HB4A (breast normal cells) and T47D (b...

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Bibliografiske detaljer
Main Authors: Badr, Haitham A., ElSayed, Abdelaleim I., Ahmed, Hafiz, Dwek, Miriam V., Li, Chen-zhong, Djansugurova, Leyla B.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3813469/
https://ncbi.nlm.nih.gov/pubmed/23912210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12010-013-0409-6
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