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A method to rapidly and accurately compare relative efficacies of non-invasive imaging reporter genes in a mouse model, and its application to luciferase reporters

PURPOSE: Our goal is to develop a simple, quantitative, robust method to compare the efficacy of imaging reporter genes in culture and in vivo. We describe an adenoviral vector-liver transduction procedure, and compare the luciferase reporter efficacies. PROCEDURES: Alternative reporter genes are ex...

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Detalles Bibliográficos
Main Authors: Gil, Jose S., Machado, Hidevaldo B., Herschman, Harvey R.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3813453/
https://ncbi.nlm.nih.gov/pubmed/21850545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-011-0515-1
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