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The role of transmembrane channel–like proteins in the operation of hair cell mechanotransducer channels

Sound stimuli elicit movement of the stereocilia that make up the hair bundle of cochlear hair cells, putting tension on the tip links connecting the stereocilia and thereby opening mechanotransducer (MT) channels. Tmc1 and Tmc2, two members of the transmembrane channel–like family, are necessary fo...

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Bibliographic Details
Main Authors: Kim, Kyunghee X., Beurg, Maryline, Hackney, Carole M., Furness, David N., Mahendrasingam, Shanthini, Fettiplace, Robert
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3813385/
https://ncbi.nlm.nih.gov/pubmed/24127526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201311068
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