FOXO1 promotes wound healing through the up-regulation of TGF-β1 and prevention of oxidative stress

Keratinocyte mobilization is a critical aspect of wound re-epithelialization, but the mechanisms that control its precise regulation remain poorly understood. We set out to test the hypothesis that forkhead box O1 (FOXO1) has a negative effect on healing because of its capacity to inhibit proliferat...

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Detalhes bibliográficos
Main Authors: Ponugoti, Bhaskar, Xu, Fanxing, Zhang, Chenying, Tian, Chen, Pacios, Sandra, Graves, Dana T.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2013
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3812981/
https://ncbi.nlm.nih.gov/pubmed/24145170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201305074
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