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Caspases determine the vulnerability of oligodendrocytes in the ischemic brain

Although oligodendrocytes (OLGs) are thought to be vulnerable to hypoxia and ischemia, little is known about the detailed mechanism by which these insults induce OLG death. From the clinical viewpoint, it is imperative to protect OLGs as well as neurons against ischemic injury (stroke), because they...

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Pubblicato in:J Clin Invest
Autori principali: Shibata, Mamoru, Hisahara, Shin, Hara, Hideaki, Yamawaki, Takemori, Fukuuchi, Yasuo, Yuan, Junying, Okano, Hideyuki, Miura, Masayuki
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2000
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC381288/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10974017/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI10203
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