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Long-Circulating Heparin-Functionalized Magnetic Nanoparticles for Potential Application as a Protein Drug Delivery Platform

Starch-coated, PEGylated and heparin-functionalized iron oxide magnetic nanoparticles (DNPH) were successfully synthesized and characterized in detail. The PEGylation (20 kDa) process resulted in an average coating of 430 PEG molecules per nanoparticle. After that, heparin conjugation was carried ou...

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Detalhes bibliográficos
Main Authors: Zhang, Jian, Shin, Meong Cheol, David, Allan E., Zhou, Jie, Lee, Kyuri, He, Huining, Yang, Victor C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3812800/
https://ncbi.nlm.nih.gov/pubmed/24024964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp400360q
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