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Tracking 20 Years of Compound-to-Target Output from Literature and Patents

The statistics of drug development output and declining yield of approved medicines has been the subject of many recent reviews. However, assessing research productivity that feeds development is more difficult. Here we utilise an extensive database of structure-activity relationships extracted from...

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Autores principales: Southan, Christopher, Varkonyi, Peter, Boppana, Kiran, Jagarlapudi, Sarma A.R.P., Muresan, Sorel
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3812171/
https://ncbi.nlm.nih.gov/pubmed/24204758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077142
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