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Critical Role of TLR4 in Human Metapneumovirus Mediated Innate Immune Responses and Disease Pathogenesis

Human metapneumovirus (hMPV) is one of the main causes of acute respiratory tract infections in children, elderly and immunocompromised patients. The mammalian Toll-like receptors (TLR) were identified as critical regulators of innate immunity to a variety of microbes, including viruses. We have rec...

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Detalhes bibliográficos
Main Authors: Velayutham, Thangam Sudha, Kolli, Deepthi, Ivanciuc, Teodora, Garofalo, Roberto P., Casola, Antonella
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3812158/
https://ncbi.nlm.nih.gov/pubmed/24205331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078849
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