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The Impact of Gene Expression Variation on the Robustness and Evolvability of a Developmental Gene Regulatory Network

Regulatory interactions buffer development against genetic and environmental perturbations, but adaptation requires phenotypes to change. We investigated the relationship between robustness and evolvability within the gene regulatory network underlying development of the larval skeleton in the sea u...

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Detalhes bibliográficos
Main Authors: Garfield, David A., Runcie, Daniel E., Babbitt, Courtney C., Haygood, Ralph, Nielsen, William J., Wray, Gregory A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3812118/
https://ncbi.nlm.nih.gov/pubmed/24204211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001696
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