Deletion of IL-4 Receptor Alpha on Dendritic Cells Renders BALB/c Mice Hypersusceptible to Leishmania major Infection

In BALB/c mice, susceptibility to infection with the intracellular parasite Leishmania major is driven largely by the development of T helper 2 (Th2) responses and the production of interleukin (IL)-4 and IL-13, which share a common receptor subunit, the IL-4 receptor alpha chain (IL-4Rα). While IL-...

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Detalhes bibliográficos
Main Authors: Hurdayal, Ramona, Nieuwenhuizen, Natalie E., Revaz-Breton, Mélanie, Smith, Liezel, Hoving, Jennifer C., Parihar, Suraj P., Reizis, Boris, Brombacher, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3812013/
https://ncbi.nlm.nih.gov/pubmed/24204259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003699
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