Metformin Attenuates the Exacerbation of the Allergic Eosinophilic Inflammation in High Fat-Diet-Induced Obesity in Mice

A positive relationship between obesity and asthma has been well documented. The AMP-activated protein kinase (AMPK) activator metformin reverses obesity-associated insulin resistance (IR) and inhibits different types of inflammatory responses. This study aimed to evaluate the effects of metformin o...

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Autori principali: Calixto, Marina Ciarallo, Lintomen, Letícia, André, Diana Majoli, Leiria, Luiz Osório, Ferreira, Danilo, Lellis-Santos, Camilo, Anhê, Gabriel Forato, Bordin, Silvana, Landgraf, Richardt Gama, Antunes, Edson
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811997/
https://ncbi.nlm.nih.gov/pubmed/24204674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076786
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