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Selective ablation of lung epithelial IKK2 impairs pulmonary Th17 responses and delays the clearance of Pneumocystis

Pneumocystis is an atypical fungal pathogen which causes severe, often fatal pneumonia (PcP) in immunocompromised patients. Healthy humans and animals also encounter this pathogen, but generate a protective CD4(+) T cell dependent immune response that clears the pathogen with little evidence of dise...

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Detalhes bibliográficos
Main Authors: Perez-Nazario, Nelissa, Rangel-Moreno, Javier, O’Reilly, Michael A., Pasparakis, Manolis, Gigliotti, Francis, Wright, Terry W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811920/
https://ncbi.nlm.nih.gov/pubmed/24078701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301679
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