Characterization of Botulinum Neurotoxin A Subtypes 1 Through 5 by Investigation of Activities in Mice, in Neuronal Cell Cultures, and In Vitro

Botulinum neurotoxins (BoNTs) are synthesized by Clostridium botulinum and exist as seven immunologically distinct serotypes designated A through G. For most serotypes, several subtypes have now been described based on nominal differences in the amino acid sequences. BoNT/A1 is the most well-charact...

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Detalhes bibliográficos
Main Authors: Whitemarsh, Regina C. M., Tepp, William H., Bradshaw, Marite, Lin, Guangyun, Pier, Christina L., Scherf, Jacob M., Johnson, Eric A., Pellett, Sabine
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811745/
https://ncbi.nlm.nih.gov/pubmed/23918782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00536-13
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