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Cloning and Heterologous Expression of the Thioviridamide Biosynthesis Gene Cluster from Streptomyces olivoviridis

Thioviridamide is a unique peptide antibiotic containing five thioamide bonds from Streptomyces olivoviridis. Draft genome sequencing revealed a gene (the tvaA gene) encoding the thioviridamide precursor peptide. The thioviridamide biosynthesis gene cluster was identified by heterologous production...

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Bibliografiske detaljer
Main Authors: Izawa, Masumi, Kawasaki, Takashi, Hayakawa, Yoichi
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811549/
https://ncbi.nlm.nih.gov/pubmed/23995943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01978-13
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